The East Stroudsburg University Business Accelerator, located in the Pocono Mountains Keystone Innovation Zone, officially opened in December 2001 to encourage economic growth and entrepreneurship. The Program provides start–ups with a variety of business support services, faculty expertise and student interns. The program focuses on building a more diversified business base, increasing high–tech job opportunities and contributing to economic and community development.

The Business Accelerator Program focuses on:

• Homeland Security
• Information Technology
• Biotechnology/Life Sciences
• Healthcare
• Advanced Manufacturing
• Financial Services
• Other area that support the university's academic programs

Currently, seven companies are located in the Accelerators:

• Baldon Computer Solutions, LLC
• Cinch Creative Media, LLC
• Right Reason Technologies, LLC
• Grad Techs, LLC
• A Sound Strategy, Inc.
• Nadig Staircases, Inc.
• FD Software Enterprises
• ABP Software, LLC
• DMI Manufacturing, Inc.